2. Biological Models and Treatments

About this Lecture

Lecture

In this lecture, we think about different biological models of depression and available drug treatments, focusing in particular on: (i) the biological factors that are thought to contribute to depression, including monoamine levels in the brain, genetics, physical illness and hippocampal atrophy; (ii) the different drugs used to treat depression, including monoamine oxidase inhibitors, tricyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs); (iii) electroconvulsive therapy (ECT) as an alternative biological treatment for depression.

Course

In this course, Professor Linda Gask (University of Manchester) explores the topic of depression. In the first lecture, we think about what depression is and how it can be diagnosed. In the second lecture, we think about different biological explanations for depression and consider available drug treatments. In the third lecture, we think about Freud’s psychodynamic model of depression. Next, we think about two cognitive models and their corresponding treatments: Ellis’s ABC Model and Rational Emotive Therapy and Beck’s Cognitive Triad and Cognitive Behavioural Therapy. In the fifth lecture, we introduce Seligman’s Learned Helplessness theory as a further psychological explanation for depression. In the sixth and final lecture, we conclude the course with a discussion of the social factors that may play a role in depression and underlines the importance of considering biological, psychological and social factors in conjunction.

Lecturer

Professor Linda Gask trained in medicine at the University of Edinburgh and in psychiatry in the North West of England. She was a 2000-2001 Harkness Fellow in Health Care Policy based at the Center for Health Studies in Seattle. She has also worked as a consultant for the World Health Organisation and has been a zonal representative for the World Psychiatric Association.